Table 3 |
|||
|
Characteristics of QTc interval |
|||
| Group 1 (N = 32) |
Group 2 (N = 29) |
||
| Characteristic |
Patients in monotherapy |
Patients in polytherapy |
*p |
|
|
|||
| QTc I, mean ± SD (ms) |
439 ± 22 |
439 ± 22 |
0.953 |
| QTc II, mean ± SD (ms) |
439 ± 24 |
440 ± 20 |
0.878 |
| ***p |
0.989 |
0.812 |
|
| QTc prolongation, mean ± SD (ms) |
8 ± 17 |
9 ± 19 |
0.840 |
| **p |
|||
|
|
|||
| QTc I > 450 ms, N (%) |
12 (37.5) |
10 (34.5) |
1.000 |
| QTc II > 450 ms, N (%) |
10 (31.3) |
9 (31.0) |
1.000 |
| QTc I 451–470 ms, N (%) |
11 (34.4) |
8 (27.6) |
0.593 |
| QTc II 451–470 ms, N (%) |
6 (18.7) |
7 (24.1) |
0.757 |
| QTc I > 470 ms, N (%) |
1 (3.1) |
2 (6.9) |
0.600 |
| QTc II > 470 ms, N (%) |
4 (12.5) |
2 (6.9) |
0.674 |
| QTc II – QTc I > 30 ms, N (%) |
3 (9.4) |
3 (10.3) |
1.000 |
|
*p – 2-tailed unpaired t test; **p – 2-tailed Fisher Exact test; ***p – 2-tailed paired t test; QTc I – baseline QTc; QTc II – QTc after two weeks of treatment | |||
Sumić et al. Annals of General Psychiatry 2007 6:13 doi:10.1186/1744-859X-6-13 |
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