Table 5 |
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Effect of chronic dioscorea administration on IL-2 levels in the brain |
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| OVX |
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|
|
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| Sham |
LA rats |
HA rats |
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|
|
|
|
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| 0 mg/kg (n = 10) |
250 mg/kg (n = 11) |
750 mg/kg (n = 9) |
0 mg/kg (n = 8) |
250 mg/kg (n = 10) |
750 mg/kg (n = 9) |
1 500 mg/kg (n = 7) |
0 mg/kg (n = 7) |
250 mg/kg (n = 7–8) |
750 mg/kg (n = 9) |
1 500 mg/kg (n = 10) |
|
|
|
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| Prefrontal cortex |
2.4 ± 0.2 |
2.7 ± 0.3 |
2.4 ± 0.2 |
1.7 ± 0.2# |
2.5 ± 0.1* |
2.2 ± 0.3 |
1.8 ± 0.3 |
1.9 ± 0.2 |
2.1 ± 0.2 |
2.3 ± 0.3 |
2.2 ± 0.2 |
| Cerebral cortex |
1.9 ± 0.4 |
1.8 ± 0.3 |
1.3 ± 0.2 |
1.6 ± 0.2 |
1.8 ± 0.3 |
2.1 ± 0.4 |
1.7 ± 0.2 |
2.7 ± 0.6 |
1.5 ± 0.2* |
1.5 ± 0.2** |
1.4 ± 0.2** |
|
LA, low anxiety; HA, high anxiety. #, p < 0.05, compared to the untreated sham-operated rats; *, p < 0.05; **, p < 0.01, compared to the untreated rats in the same anxiety category. The data are expressed as the mean ± SEM. The units are pg/μg protein. | |||||||||||
Ho et al. Annals of General Psychiatry 2007 6:21 doi:10.1186/1744-859X-6-21 |
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