Table 5

Effect of chronic dioscorea administration on IL-2 levels in the brain





OVX






Sham
LA rats
HA rats





0 mg/kg (n = 10)
250 mg/kg (n = 11)
750 mg/kg (n = 9)
0 mg/kg (n = 8)
250 mg/kg (n = 10)
750 mg/kg (n = 9)
1 500 mg/kg (n = 7)
0 mg/kg (n = 7)
250 mg/kg (n = 7–8)
750 mg/kg (n = 9)
1 500 mg/kg (n = 10)

Prefrontal cortex
2.4 ± 0.2
2.7 ± 0.3
2.4 ± 0.2
1.7 ± 0.2#
2.5 ± 0.1*
2.2 ± 0.3
1.8 ± 0.3
1.9 ± 0.2
2.1 ± 0.2
2.3 ± 0.3
2.2 ± 0.2
Cerebral cortex
1.9 ± 0.4
1.8 ± 0.3
1.3 ± 0.2
1.6 ± 0.2
1.8 ± 0.3
2.1 ± 0.4
1.7 ± 0.2
2.7 ± 0.6
1.5 ± 0.2*
1.5 ± 0.2**
1.4 ± 0.2**

LA, low anxiety; HA, high anxiety. #, p < 0.05, compared to the untreated sham-operated rats; *, p < 0.05; **, p < 0.01, compared to the untreated rats in the same anxiety category. The data are expressed as the mean ± SEM. The units are pg/μg protein.

Ho et al. Annals of General Psychiatry 2007 6:21   doi:10.1186/1744-859X-6-21

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