Table 3

Differences in blood oxygenated level dependent (BOLD) response between the two groups during the sustained attention, selective attention and divided attention tasks

Max z-score
 TLRC co-ordinates
 BA
Sustained attention:


HP > POC


R inferior parietal lobe
 3.8
 [42 -58 48]
 7
R subcallosal gyrus
 3.7
 [16 20 -13]
 11
R superior parietal lobe
 3.6
 [30 -64 54]
 7
R mid-occipital gyrus
 3.3
 [38 -92 -4]
 18
R mid-occipital gyrus
 3.2
 [28 -96 1]
 18
R mid-temporal gyrus
 3.2
 [48 -20 -12]
 21
R posterior cingulate gyrus
 3.1
 [26 -64 12]
 31
R superior frontal gyrus
 3.0
 [18 62 1]
 10
R lingual gyrus
 3.0
 [32 -60 -5]
 19
R parahippocampal gyrus/entorhinal cortex
 2.9
 [24 -10 -30]
 28
L ventral striatum
 2.9
 [-17 11 -9]
 -
L cuneus
 2.9
 [-24 -78 12]
 18
R precentral gyrus
 2.4
 [50 -8 22]
 43
R precentral gyrus
 2.8
 [34 22 38]
 9
R lingual gyrus
 2.8
 [4 -94 -5]
 18
POC > HP


L superior temporal gyrus
 3.5
 [-64 -52 8]
 21
L superior frontal gyrus
 2.9
 [-22 56 31]
 9
R mid-temporal gyrus
 2.8
 [54 -74 18]
 19
Selective attention:


HP > POC


R cingulate gyrus
 4.2
 [24 -46 38]
 31
R cuneus
 4.1
 [26 -88 8]
 18
R parahippocampal gyrus
 3.7
 [38 -48 -9]
 19
R precuneus
 3.3
 [14 -70 36]
 7
R mid-frontal gyrus
 3.3
 [36 56 1]
 10
R insula
 3.0
 [40 -4 -5]
 13
R fusiform gyrus
 3.0
 [34 -72 -20]
 19
R caudate
 3.0
 [14 6 20]
 -
L insula
 3.0
 [-44 -10 0]
 13
R globus pallidus
 2.9
 [22 -14 -2]
 -
R inferior frontal gyrus
 2.9
 [40 18 -12]
 47
POC > HP


R mid-temporal gyrus
 4.3
 [72 -28 -4]
 21
L mid-temporal gyrus
 4.2
 [-46 -72 20]
 39
R mid-temporal gyrus
 3.7
 [70 -42 0]
 21
L mid-frontal gyrus
 3.5
 [-18 66 26]
 10
L superior frontal gyrus
 3.4
 [-24 42 34]
 10
L supramarginal gyrus
 3.0
 [-56 -42 36]
 40
R parahippocampal gyrus
 3.0
 [30 -24 -18]
 36
R mid-temporal gyrus
 3.0
 [56 0 -34]
 21
L mid-frontal gyrus
 3.0
 [-54 28 30]
 9
Dual attention:


HP > POC


L inferior frontal gyrus
 4.0
 [-24 14 -22]
 47
L mid-temporal gyrus
 3.8
 [-40 -44 1]
 19
L inferior parietal lobe
 3.8
 [-32 -40 26]
 13
L medial frontal gyrus
 3.6
 [-6 40 44]
 8
L superior temporal gyrus
 3.6
 [-46 20 -28]
 38
R medial frontal gyrus
 3.7
 [10 32 46]
 8
R inferior frontal gyrus
 3.3
 [54 42 12]
 46
R mid-occipital gyrus
 3.3
 [30 -72 4]
 18
L parahippocampal gyrus
 3.2
 [-20 -10 -23]
 35
R hypothalamus
 3.1
 [8 -6 -9]
 -
R precuneus
 3.1
 [24 -50 44]
 7
L cingulate gyrus
 3.0
 [-22 -22 40]
 24
L parahippocampal gyrus
 2.8
 [-22 -34 -9]
 30
R mid-frontal gyrus
 2.8
 [42 62 -4]
 10
POC > HP


R mid-temporal gyrus
 3.3
 [58 -68 18]
 39
L superior temporal gyrus
 3.1
 [-40 -6 -12]
 21
L culmen
 3.0
 [-20 -40 -22]
 -

Foci of significantly greater activation during the attention tasks when the groups were compared (only peaks with z > 2.8 reported here). Localisation, Tailarach co-ordinates (TLRC) and corresponding Brodmann areas (BA) represents the voxel with the maximum z-score; HP, healthy participants; L, left; POCs, presumed obligate carriers; R, right.

Filbey et al. Annals of General Psychiatry 2008 7:18   doi:10.1186/1744-859X-7-18
Open Data