Table 1 |
||||
|
Percentage of convulsing mice following the intraperitoneal administration of bupropion HCl and bupropion metabolites in mice |
||||
| Dose* (mg/kg) |
Bupropion HCl |
Erythrohydrobupropion HCl |
Threohydrobupropion HCl |
Hydroxybupropion HCl |
|
|
||||
| 25 |
0% |
0% |
0% |
0% |
| 50 |
0% |
10% |
50% |
100% |
| 75 |
10% |
90% |
100% |
100% |
|
*10 mice per dose per treatment. | ||||
Silverstone et al. Annals of General Psychiatry 2008 7:19 doi:10.1186/1744-859X-7-19 |
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