Table 2

Global brain volumes

Global brain volumes
Control groupa
(n = 18)
EOS groupa
(n = 18)
Group difference
(%)
t
p Value

Whole brain (ml)
1,325.7 (106.4)
1,290.0 (47.4)
2.7 (Control > EOS)
1.302
0.205
Grey matter (ml)
657.2 (60.4)
621.3 (29.5)
5.5 (Control > EOS)
2.271
0.032
White matter (ml)
496.5 (46.9)
476.9 (19.7)
3.9 (Control > EOS)
1.638
0.115
CSF (ml)
172.0 (20.3)
191.8 (21.9)
11.5 (EOS > Control)
-2.813
0.008
Grey matter/whole brain ratio
0.50 (0.01)
0.48 (0.02)
4.0 (Control > EOS)
2.814
0.009
White matter/whole brain ratio
0.37 (0.01)
0.37 (0.01)
0
1.314
0.199
CSF/whole brain ratio
0.13 (0.02)
0.15 (0.01)
15.4 (EOS > Control)
-3.507
0.001

aValues are given as the mean (SD).

CSF, cerebrospinal fluid; EOS, early onset schizophrenia; SD, standard deviation.

Yoshihara et al. Annals of General Psychiatry 2008 7:25   doi:10.1186/1744-859X-7-25

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