Table 3 |
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|
Effect of bupropion HCl 120 mg/kg intraperitoneal infusion times on the mean ± SD bupropion HCl-induced convulsions per mouse |
|||
| Group* |
Intraperitoneal (IP) infusion time (min) |
Total no. of convulsions |
Mean ± SD convulsions per mouse |
|
|
|||
| 1 |
0 (bolus) |
155 |
15.5 ± 22.4 |
| 2 |
15 |
272 |
27.2 ± 39.5 |
| 3 |
30 |
161 |
16.1 ± 22.2 |
| 4 |
60 |
170 |
17.0 ± 22.8 |
| 5 |
90 |
0 |
0 |
| 6 |
120 |
34 |
3.4 ± 10.4 |
| 7 |
240 |
0 |
0 |
|
*Number of mice was 10 for each group, except group 5 that had 9 mice. | |||
Silverstone et al. Annals of General Psychiatry 2008 7:27 doi:10.1186/1744-859X-7-27 |
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