Recognizing thyrotoxicosis in a patient with bipolar mania: a case report

Catherine See-Ning Lee¹^,2 and Burton Hutto¹

¹Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA

²Dorthea Dix Hospital, Raleigh, NC, USA

author email corresponding author email

Annals of General Psychiatry 2008, 7:3doi:10.1186/1744-859X-7-3


Published:	19 February 2008

Abstract

Background

A thyroid stimulating hormone level is commonly measured in patients presenting with symptoms of mania in order to rule out an underlying general medical condition such as hyperthyroidism or thyrotoxicosis. Indeed, many cases have been reported in which a patient is initially treated for bipolar mania, but is later found to have a thyroid condition. Several case reports have noted the development of a thyroid condition in bipolar patients either on lithium maintenance treatment or recently on lithium treatment.

Case presentation

We review a case in which a patient with a long history of bipolar disorder presents with comorbid hyperthyroidism and bipolar mania after recent discontinuation of lithium treatment.

Conclusion

Physicians should consider a comorbid hyperthyroidism in bipolar manic patients only partially responsive to standard care treatment with a mood stabilizer and antipsychotic.