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<art>
   <ui>1744-859X-7-S1-S246</ui>
   <ji>1744-859X</ji>
   <fm>
      <dochead>Poster presentation</dochead>
      <bibl>
         <title>
            <p>Objectively measured sleep quality and functional impairment in family caregivers of older adults with memory disorders</p>
         </title>
         <aug>
            <au id="A1" ca="yes">
               <snm>Spira</snm>
               <fnm>Adam</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A2">
               <snm>Friedman</snm>
               <fnm>Leah</fnm>
               <insr iid="I2"/>
               <insr iid="I4"/>
            </au>
            <au id="A3">
               <snm>Haagenson</snm>
               <fnm>Laura</fnm>
               <insr iid="I2"/>
               <insr iid="I4"/>
            </au>
            <au id="A4">
               <snm>Sheikh</snm>
               <fnm>Javaid</fnm>
               <insr iid="I2"/>
               <insr iid="I3"/>
               <insr iid="I4"/>
            </au>
            <au id="A5">
               <snm>Yesavage</snm>
               <fnm>Jerome</fnm>
               <insr iid="I2"/>
               <insr iid="I3"/>
               <insr iid="I4"/>
            </au>
         </aug>
         <insg>
            <ins id="I1">
               <p>Division of Geriatrics and Department of Psychiatry, University of California, San Francisco, USA</p>
            </ins>
            <ins id="I2">
               <p>Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA</p>
            </ins>
            <ins id="I3">
               <p>Veterans Affairs Palo Alto Health Care System, CA, USA</p>
            </ins>
            <ins id="I4">
               <p>Department of Veterans Affairs Sierra Pacific Mental Illness Research, Education, and Clinical Center (MIRECC)</p>
            </ins>
         </insg>
         <source>Annals of General Psychiatry</source>
         <supplement>
            <title>
               <p>International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour</p>
            </title>
            <note>Meeting abstracts - A single PDF containing all abstracts in this Supplement is available <a href="http://www.biomedcentral.com/content/files/pdf/1744-859X-7-S1-full.pdf">here</a>.</note>
         </supplement>
         <conference>
            <title>
               <p>International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour</p>
            </title>
            <location>Thessaloniki, Greece</location>
            <date-range>28 November &#8211; 2 December 2007</date-range>
            <url>http://www.psychiatry.gr</url>
         </conference>
         <issn>1744-859X</issn>
         <pubdate>2008</pubdate>
         <volume>7</volume>
         <issue>Suppl 1</issue>
         <fpage>S246</fpage>
         <url>http://www.annals-general-psychiatry.com/content/7/S1/S246</url>
         <xrefbib>
            <pubid idtype="doi">10.1186/1744-859X-7-S1-S246</pubid>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>17</day>
               <month>04</month>
               <year>2008</year>
            </date>
         </pub>
      </history>
      <cpyrt>
         <year>2008</year>
         <collab>Spira et al.; licensee BioMed Central Ltd.</collab>
      </cpyrt>
   </fm>
   <bdy>
      <sec>
         <st>
            <p>Background</p>
         </st>
         <p>Poor sleep quality has been linked to functional impairment in several populations <abbrgrp><abbr bid="B1">1</abbr><abbr bid="B2">2</abbr><abbr bid="B3">3</abbr><abbr bid="B4">4</abbr></abbrgrp> but this association has not been investigated widely in family caregivers of older adults with memory disorders. We investigated the association between objectively measured sleep and functional status in a sample of family caregivers.</p>
      </sec>
      <sec>
         <st>
            <p>Materials and methods</p>
         </st>
         <p>Participants were 42 caregiver-patient dyads. Caregivers completed the Beck Depression Inventory (BDI-II) <abbrgrp><abbr bid="B5">5</abbr></abbrgrp> and the Medical Outcomes Study SF-36 <abbrgrp><abbr bid="B6">6</abbr></abbrgrp>. The &#8220;physical function&#8221; subscale of the SF-36 measures difficulty lifting groceries, climbing stairs, etc. Scores range from 1 to 100; higher scores indicate better function. Caregivers completed 1 week of actigraphy&#8211;an objective means of measuring sleep by recording movement. We calculated their total sleep time (TST; mean time asleep while in bed) and sleep efficiency (SE; mean percentage of time asleep while in bed).</p>
      </sec>
      <sec>
         <st>
            <p>Results</p>
         </st>
         <p>Caregivers' mean age was 69.4 &#177;13.6 years. Patients' mean age was 79.8 &#177;7.6 years; their mean Mini-Mental State Exam <abbrgrp><abbr bid="B7">7</abbr></abbrgrp> score was 21.3 &#177; 4.9. Caregivers' mean physical function score was 72.6 &#177;23.2. In regression analyses (adjusted for age, self-rated health, and BDI-II), each 1-hour increase in TST was associated with a 5.7-point increase in physical function (Beta=5.71, p=.001, R-squared=.75), and each 10% increase in SE predicted a 3.8-point increase in physical function (Beta=3.79, p=.02, R-squared=.69).</p>
      </sec>
      <sec>
         <st>
            <p>Conclusions</p>
         </st>
         <p>In family caregivers, greater TST and SE were independently associated with better physical function after controlling for potential confounders. Future, longitudinal studies are needed to establish the directions of these relationships and to evaluate whether poor sleep might be a preventable cause of disability in caregivers.</p>
      </sec>
   </bdy>
   <bm>
      <ack>
         <sec>
            <st>
               <p>Acknowledgements</p>
            </st>
            <p>Research supported by the Medical Research Service of the Palo Alto Veterans Affairs Health Care System, by the Department of Verterans Affairs Sierra Pacific MIRECC, and by AG21134.</p>
         </sec>
      </ack>
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</art>
